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Botulinum Toxin - 10 Vials x 150 IU

Botulinum Toxin - 10 Vials x 150 IU
Package: 10 Vials x 150 IU

Usage: Injectable

Botox (Botulinum toxin type A) is used cosmetically to improve facial wrinkles,also to treat strabismus,spasm of the eyelids,blepharospasm,severe underarm sweating, etc.

Produced by: China


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Botulinum Toxin type A 150 IU, Buy Botulinum Toxin type A 150 IU Online


Brand name: Botulinum Toxin 150 IU, BTXA;
Generic name: Botulinum Toxin;
Active ingredient: botulinum toxin type A;
Inactive ingredients: human albumin and sodium chloride;
Manufacturer: China;
BTXA (Botulinum Toxin Type A for Therapy)

DESCRIPTION:
Botulinum Toxin Type A is type-A toxin that contains 150 IU in one vial and can be indicated into one man. Botulinum Toxin Type A is a category of preparation to correct small folds and shrink the face.
This injection is a sterile, lyophilized form of refined botulinum toxin type A, manufactured from the basic toxin of the culture of the Hall strain of Clostridium botulinum grown in a medium having trypticase as well yeast extract. A series of refining technique were extracted to form a clear complex containing of the active high molecular weight toxin protein as well as an linked hemagglutinin. After re-diluted and dialyzed the crystal clear toxin, a correct quantity of the sterilized clarified (0.2 microns) toxin were added to a solution holding gelatin-dextran-sucrose, and then lyophilized. Each vial of BTXA has 100 or 50 units (U) of C. botulinum toxin type A, 5 mg of gelatin, 25 mg of dextran and 25 mg of sucrose.

SUGGESTIONS:
This injection is gived for the therapy of blepharospasm, hemi facial tremor in adults and some forms of strabismus, especially for acute paralytic strabismus, comitant strabismus, strabismus instigated by endocrine myopathy also strabismus which cannot be fixed by operation. Anti-Wrinkle, Thin expressions and legs.

USAGE AND MEASURE:
1. Site for inoculation:
- For blepharospasm: the inoculation must be administrated intramuscularly at number of locations of upper also lower covers, i.e., using 4 to 5 places of insertion into orbicularis oculi of medial and lateral or lateral canthus temporal.
- For hemi facial tremor: besides the points mentioned above, three other places on middle, lower face and cheek should be inoculated intramuscularly. BTXA (Botulinum Toxin Type A for Therapy) may be given at the points of two sides of eyebrow, upper lip or the lower jaw agreeing to the illnesses.
- For strabismus: the BTXA (Botulinum Toxin Type A for Therapy) is inoculated using a coaxial electrode syringe with electromyography supervision or amplifier under topical anesthesia of 0.5% Decarine. The injections into additional ocular muscles are selected agreeing to the variety as well lacation of strabismus.

2. Dosage:
150 IU must be dissolved into 2.0-2.5ml sterilized water before administrating.
Dilute with sterile normal saline agreeing to different necessities before inserting. The white loose product changes to be colorless or yellowish clear solution after the reconstitution.
- For blepharopasm also hemi facial tremor: the insertion could be suggested following above directions. The primary dosage of each point is 2.5 U/ 0.05ml or 2.5 U / 0.1 ml. If the first handling is considered insufficient 1 week later, an additional insertion could be given. Dual measure of 5 U / 0.1 ml can be indicated to recrudescent people. But the limitation of total dosage of 55 U for one injection and 200 U for 1 month have to not be exceeded.
- For strabismus: for vertical as well horizontal muscle strabismus of less than 20 prism diopters, the first measure into each muscle is 1.25-2.5 U; for horizontal strabismus of 20-40 prism diopters, the first dose into every muscle is 2.5 U; for horizontal strabismus of 40-50 prism diopters, the primary dose into each muscle is 2.5 U also can be rised (to 5.0 each time) depending on the reply; for persistent VI cranial nerve paralysis lasted for more than one month. The inoculating volume into each muscle must not more 0.1 ml. To individuals, having insufficient reaction, additional insertion may be given. To recrudescent people, the dose can be repeated or amplified irregularly. But for every muscle the maximum dosage must be less than 5 U / inj.

The Thinning of BTXA:
The dilution of this medication with sterile normal saline must be prepared carefully on the basis of real desires. Following is a reference table of dissolving to be suggested. The vial has to be shaking smoothly after adding sterile normal saline to the whole dissolving. The dilution BTXA must be injected at once or maintained in refrigerator at 2 to 8 degrees and to be administrated within 4 hours. The ampule and the needle used with this medication also the lasting BTXA solution should be disposed after sterilization.

UNEXPECTED REACTIONS:
Passing ptosis of the eyelid, problem of the minor eyelid, minimized blinking, eyelid close moderately, dimless of facial muscles, etc. may happen to a few patients who take BTXA healing for blepharospasm as well hemi facial tremor. But, all the indications will vanish without any remedy within 3 to eight weeks. Passing also diverse degree of ptosis of the eyelid, vertical deviance also seldom mydriasis, which allied to the diffusion of the toxin to the muscles nearby, may happen to some people who take BTXA (Botulinum Toxin Type A for Therapy) remedy for strabismus. The symptoms will vanish without any treatment within a few weeks.

CONTRAINDICATIONS:
BTXA (Botulinum Toxin Type A for Therapy) is not recommended in patients with anaphylactic structure and known allergy to this product.

WARNINGS:
The insertion way must be taken later to persons who have temperature, acute infectious illness and carefully to the individuals with heart, liver, lung malady, active tuberculosis, blood illness as well pregnant women.
Botulinum toxin may be potentiated by aminoglycoside antibiotics (such as gentamicin).This kind of medications must not be taken during the using of BTXA (Botulinum Toxin Type A for Therapy).
BTXA (Botulinum Toxin Type A for Therapy) is in minim reaction or without any effect to the patients in the next situations: strabismus above 50 prism diopters, fixed strabismus, strabismus caused by extremely corrected surgery, chronic paralysis strabismus, as well as chronic VI or III cranial nerve paralysis, severe muscle fiber contracture.
1:1000 adrenalines have to be set in case of occasional accident.

SHELF LIFE:
Three years from the day of lyophilization. The action is clear and can be last 6 months.

STORAGE:
Store at a temperature of -5 to -20 gr C (23 to -4 gr F). Keep unopened vial at -5 temperatures.

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